After graduating from Harvard University with honors, Dr. DiMeglio obtained her MD from the University of Pennsylvania in Philadelphia, PA and performed her residency in Pediatrics at Children’s Memorial Hospital (Northwestern University) in Chicago, IL.  She completed her fellowship in Pediatric Endocrinology and received her Master’s in Public Health from Indiana University-Purdue University, Indianapolis.  Since her fellowship, Dr. DiMeglio has been working in clinical research with a focus on Type 1 diabetes prevention and treatments, including new technologies and therapies for metabolic bone disease.  She currently directs Riley Hospital’s participation in a number of type 1 diabetes research networks and supervises a research staff of 5 nurses and three technicians.  She also collaborates on a variety of other translational and clinical research projects.  She is an active clinician, seeing patients with diabetes and endocrine disorders in clinics, and she teaches medical students, residents, housestaff, and fellows.

Research interests include different pathophysiologic processes affecting beta cell function in Type 1 and Type 2 Diabetes; clinical interests include pediatric endocrinology and diabetes. I am originally from the Southeast, but have enjoyed living in the Midwest with my husband and two sons, and becoming a part of the Riley community.

The long-range goal of the Evans-Molina lab is to define the pathways that govern beta cell function in states of health in order to understand how these regulatory circuits are impaired in the pathologic state of Type 2 diabetes mellitus. The major focus of the lab is to characterize changes in expression and activity of the sarco-endoplasmic reticulum Ca2+ ATPase or SERCA pump in the diabetic beta cell and to identify the downstream effects of SERCA dysregulation on ER calcium homeostasis, insulin production and secretion, and beta cell survival.

Dr. Ismail attended medical school in Cairo, Egypt. She earned her MBBCh (MD) degree with honors from Cairo University, Faculty of Medicine in 1999. She completed her residency and pediatric endocrine training at Cairo University Children’s Hospital. Dr. Ismail later moved to the United States where she completed her US residency training at T.C. Thompson Children’s Hospital in Chattanooga, TN and her pediatric endocrine fellowship training at Seattle Children’s Hospital. Dr. Ismail became the Clinical Director of the Weight Management Program at Children’s Hospital of Pittsburgh in 2014 and the Clinical Director of the Diabetes Program there in 2016. Dr. Ismail joined the faculty at IU School of Medicine in 2018. She is board certified in Pediatrics as well as Pediatric Endocrinology. Dr. Ismail has a primary interest in type 1 diabetes research as well as clinical management of diabetes.