Prevention Studies

You can help us find a way to prevent type 1 diabetes.

If your screening results show you are in the early stages of T1D (Stage 1 or Stage 2), you may be able to participate in a prevention study. These studies are looking for ways to slow down or stop the disease.

In addition to the studies listed here, we are always planning future studies. If we don't currently offer a study that's right for you, you can opt in for monitoring by a TrialNet research team at the forefront of T1D research. That way, when a new study opens, you'll be among the first to know!

Current Prevention Studies

Abatacept - Closed to Enrollment - Study Ongoing

TrialNet is testing the drug abatacept to see if it can delay or prevent progression of early stage T1D (stage 1 to stage 2) and ultimately prevent clinical diagnosis (stage 3). In earlier studies for people newly diagnosed (stage 3), abatacept helped slow down disease progression. Learn more

Hydroxychloroquine (HCQ)

We are testing the drug hydroxychloroquine (HCQ) to see if it can delay or prevent early stage T1D (stage 1) from progressing to abnormal glucose tolerance (stage 2) and ultimately prevent clinical diagnosis (stage 3). HCQ is already used to reduce symptoms and progression of other autoimmune diseases, such as rheumatoid arthritis and lupus. This is the first study to see if it can prevent or delay T1D. Learn more