Mission & History

TrialNet research teams around the world are committed to advancing T1D research.


Using knowledge gained through clinical research, our mission is to prevent T1D and stop disease progression by preserving insulin production before and after diagnosis. 

Advancing knowledge of T1D

Advances in research are made possible because of people just like you. Join the more than 160,000 relatives of people with T1D who have already participated in TrialNet research. Only with help from people like you will we will continue to learn more about T1D and how to prevent it.


TrialNet was established in response to the Surgeon General's Report Healthy People 2000. This report identified diabetes as a national health objective for the United States.  In response, Congress created the Diabetes Research Working Group (DRWG) to develop a plan of action for diabetes research. One of their recommendations was to conduct additional research studies toward preventing type 1 diabetes.

As a result, the Diabetes Prevention Trial of Type 1 (DPT-1) was launched in 1994. DPT-1 was a large multicenter, randomized, controlled clinical trial to investigate the possibility of delaying or even preventing clinical onset of T1D with daily doses of insulin in individuals at risk for the disease. When the trial concluded, TrialNet was created to continue this important work and find a way to prevent T1D.  

Join us on the Pathway to Prevention.

If you have T1D in your family, you’re in a unique position to help us find a way to prevent this disease. Take the first step on the Pathway to Prevention today with free screening.

Get started today