Image of intestines with a cropped circle showing a close up view of microrganisms in the microbiome. There is also another cropped circle with a magnifying glass examining data. TrialNet logo is in the top left corner.
Research Spotlight

Exploring the fascinating connection between the gut microbiome and immune therapy

While conducting research in his lab at Yale University, TrialNet Chair Kevan Herold, MD, discovered an interesting outcome. Mouse models (mice genetically modified to mimic a human condition) treated with multiple antibiotics did not respond to the immune therapy teplizumab, the only FDA-approved treatment to delay the onset of type 1 diabetes (T1D). 

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4 poloroid photos of maisie on a blue and pink background. Maisie celebrates wearing a pump and cgm in the first photos. The last photos feature Maisie's Diabetes Link chapter and a Diabuddy stuffed animal.
Participant Spotlight

Meet Maisie Mische: Turning a T1D diagnosis into opportunities

When Maisie Mische, a 22-year-old mechanical engineering student at Marquette University, started having trouble with her vision last year, she attributed the problem to eye fatigue from late-night studying. But two episodes of double vision and subsequent tests revealed something more complex: type 1 diabetes (T1D).

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